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Alterations in skeletal muscle repair in young adults with type 1 diabetes mellitus

Ontario
29 September 2021
This research project looked at muscle regeneration in people with T1D. Eighteen physically active young adults with and without T1D were studied before and after performing an exercise that was known to cause muscle damage. The study found, among other things, that those with T1D had moderately lower strength recovery after 48 and 96 hours. Serum creatine kinase, which is an indicator of muscle damage, was also moderately higher in those with T1D when they were at rest and slightly elevated 96 hours after exercise. Overall, the findings indicate that skeletal muscle in young adults with T1D is changed after damaging exercise and they may need longer recovery times following intense exercise. As increased physical activity is recommended for those with T1D, it is important to study this topic further to see if longer periods of recovery should be taken in order to effectively repair muscle damage and avoid any health issues that could stem from this.
  • Dial AG, Grafham GK, Monaco CM, Voth J, Brandt L, Tarnopolsky MA, Hawke TJ